It's the Office365 playbook: The subscriber model is better because you can get updates quickly. We'll update the software continuously to fix bugs right away. Bugs will be a thing of the past. You'll love it!
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Here's another article interpreting Pfizer's "March" timeline as unlikely to come true. Warning if you click: Someone says "I've seen no evidence to date..." to dismiss updated vax. It's the usual suspect: he said the same for >4wk intervals and boosters scientificamerican.com/artic…
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If you read articles like below, you'd get the impression the pharma companies are motivated to roll out vax quickly. It says they even do dry runs for making new vaccines. And yet so far... no Delta, no Omicron vax. nature.com/articles/d41586-0…
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One idea that I haven't seen mentioned is the utility of building a repertoire of variant boosters. If we had that, when a future variant hits, we can select the booster that best matches even if not perfect.
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Pfizer actually saw their previously undisclosed Beta booster worked best on Omicron. They revealed that when Omicron appeared, but have stayed quiet about it since. Seems they were advertising a potential ability if asked, but were happy not to be asked.
First results of any kind about variant-specific boosters? Seems Pfizer has a lot of data they are sitting on.
Show this thread
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So while each new wave may be over before a variant booster can be made, approved, and shipped, the making and approving *will still be useful* for future waves, because you then build a broader repertoire. This would improve our ability to respond when a new variant arrives.
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Correction two tweets up: Pfizer saw their alpha, not beta, booster worked 4x better on Omicron than the actual boosters we are getting
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Here's another reason boosters that include Omicron spike are needed even after this wave passes: those who avoided Omicron so far will become spreaders and victims of an Omicron rebound in the fall. We'll need boosters of some sort for sure, so best would be Omicron+Delta mix.
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Replying to @michaelzlin
C19vitamin.com is the jest booster.

Jan 22, 2022 · 11:05 PM UTC